|Other Names||Guanine nucleotide-binding protein subunit alpha-12, G alpha-12, G-protein subunit alpha-12, GNA12|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP3315a was selected from the region of human Phospho-GNA12-S67. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. May play a role in the control of cell migration through the TOR signaling cascade.|
|Cellular Location||Membrane; Lipid-anchor.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Guanine nucleotide-binding proteins (G proteins) are modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 subunits; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
Krakstad, B.F., et al., Proc. Natl. Acad. Sci. U.S.A. 101(28):10314-10319 (2004).Hillier, L.W., et al., Nature 424(6945):157-164 (2003).Scherer, S.W., et al., Science 300(5620):767-772 (2003).Suzuki, N., et al., Proc. Natl. Acad. Sci. U.S.A. 100(2):733-738 (2003).Yamaguchi, Y., et al., J. Biol. Chem. 278(17):14936-14939 (2003).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.