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Phospho-FLNA(S2152) Antibody Blocking peptide

Synthetic peptide

Product Information
Primary Accession P21333
Clone Names 110064
Peptide ID 110064
Additional Information
Gene ID 2316
Other Names Filamin-A, FLN-A, Actin-binding protein 280, ABP-280, Alpha-filamin, Endothelial actin-binding protein, Filamin-1, Non-muscle filamin, FLNA, FLN, FLN1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP3379a was selected from the region of human Phospho-FLNA-S2151. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms FLN, FLN1
Function Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface- localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis.
Cellular Location Cytoplasm, cell cortex. Cytoplasm, cytoskeleton
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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Actin-binding protein, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.


Wang,Y., Oncogene 26 (41), 6061-6070 (2007)Lad,Y., EMBO J. 26 (17), 3993-4004 (2007)Cho,E.Y., Mol. Endocrinol. 21 (9), 2242-2254 (2007)

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$ 80.00
Cat# BP3379a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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