- Antibodies
- New
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Tag
- Peptides
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Amino Acids
- Tag
- Biological Process >
- Proteins
- RNAi
- FL cDNA Clones
- Cell/Tissues/Lysates
Phospho-PHB2-Y128 Antibody Blocking PeptideSynthetic peptide
| Country | United States
Ordering Information
Australia Austria Belgium Brazil Bulgaria Canada China Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland India Indonesia Ireland Israel Italy Japan Korea Latvia Lithuania Luxembourg Macedonia Malaysia Malta Netherlands Norway Pakistan Poland Portugal Romania Serbia Singapore Slovakia Slovenia Spain Sweden Switzerland Taiwan Turkey United Kingdom United States Vietnam Others 
|
|||
|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| BP3539a | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
Phospho-PHB2-Y128 Antibody Blocking Peptide - Product info | |
| Primary Accession | Q99623 |
| Other Accession | NP_009204 |
| Clone Names | 80130119 |
| Calculated MW | 33296 Da |
Phospho-PHB2-Y128 Antibody Blocking Peptide - Additional info | |
| Gene ID 11331 | |
| Target/Specificity The synthetic peptide sequence used to generate the antibody AP3539a was selected from the region of human Phospho-PHB2-Y128. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
Phospho-PHB2-Y128 Antibody Blocking Peptide - Protein Information | |
| Name PHB2 | |
| Synonyms BAP, REA | |
| Function Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging | |
| Cellular Location Mitochondrion inner membrane (By similarity). Cytoplasm (By similarity). Nucleus (By similarity) Note=Also cytoplasmic and nuclear (By similarity) | |
Phospho-PHB2-Y128 Antibody Blocking Peptide - Related products
AP3539a: Phospho-PHB2-Y128 Antibody
AP3622a: Phospho-PHB2-pY248 Antibody
AP7270a: REA (PHB2) Antibody (N-term)
AP7270b: REA (PHB2) Antibody (C-term)
BP3539a: Phospho-PHB2-Y128 Antibody Blocking Peptide
BP3622a: Phospho-PHB2-pY248 Antibody Blocking Peptide
BP7270a: PHB2 Antibody (N-term) Blocking Peptide
Phospho-PHB2-Y128 Antibody Blocking Peptide - Research Areas
Abgent welcomes feedback from its customers.
If you have used an Abgent product and would like to share how it has performed, please click on the
"Submit Review" button and provide the requested information. Our staff will examine and post your
review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.
Thank you for your support.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.
REFERENCES
Takata,H., Curr. Biol. 17 (15), 1356-1361 (2007)Kasashima,K., J. Biol. Chem. 281 (47), 36401-36410 (2006)
