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Phospho-NPTX1(Y344) Antibody Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P47971 |
|---|---|
| Clone Names | 80130105 |
| Gene ID | 266777 |
|---|---|
| Other Names | Neuronal pentraxin-1, NP1, 47 kDa taipoxin-binding protein, Neuronal pentraxin I, NP-I, Nptx1 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP3557a was selected from the region of human Phospho-NPTX1-pY344. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | Nptx1 |
|---|---|
| Function | May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. |
| Cellular Location | Secreted {ECO:0000250|UniProtKB:Q15818}. Cytoplasmic vesicle, secretory vesicle. Endoplasmic reticulum |
| Tissue Location | Cerebellum, hippocampus and cerebral cortex. |
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Provided below are standard protocols that you may find useful for product applications.
Background
NPTX1 is a member of the neuronal pentraxin family. Human neuronal pentraxin 1 is similar to the rat NP1, a binding protein for the snake venom toxin taipoxin.
References
Hossain,M.A., J. Neurosci. 24 (17), 4187-4196 (2004)Schlimgen,A.K., Neuron 14 (3), 519-526 (1995)
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