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Phospho-S100A11(Y32) Antibody Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P31949
Clone Names 80118194
Additional Information
Gene ID 6282
Other Names Protein S100-A11, Calgizzarin, Metastatic lymph node gene 70 protein, MLN 70, Protein S100-C, S100 calcium-binding protein A11, Protein S100-A11, N-terminally processed, S100A11, MLN70, S100C
Target/Specificity The synthetic peptide sequence used to generate the antibody AP3601a was selected from the region of human Phospho-S100A11-pY32. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name S100A11
Synonyms MLN70, S100C
Function Facilitates the differentiation and the cornification of keratinocytes.
Cellular Location Cytoplasm. Nucleus
Research Areas
Citations (0)
citation

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Background

Protein S100-A11 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.

References

Howell,M.D., J. Invest. Dermatol. 128 (9), 2248-2258 (2008)Cecil,D.L., J. Immunol. 180 (12), 8378-8385 (2008)Sakaguchi,M., J. Cell Biol. 163 (4), 825-835 (2003)

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$ 277.78
Cat# BP3601a
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