|Other Names||Claudin-2, SP82, CLDN2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP3639a was selected from the region of human Phospho-CLDN2-pY224. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity.|
|Cellular Location||Cell junction, tight junction. Cell membrane; Multi-pass membrane protein|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions.
Morita,K., Proc. Natl. Acad. Sci. U.S.A. 96 (2), 511-516 (1999)Furuse,M., J. Cell Biol. 141 (7), 1539-1550 (1998)
If you have any additional inquiries please email technical services at firstname.lastname@example.org.