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hH4-K20 (Methyl 2) Antibody Blocking PeptideSynthetic peptide

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United States
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Ordering Information
Catalog # Size Availability Price  
BP3674a 0.1 mg 400 ul In Stock $ 45.00 Add to cart
  • Specification
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hH4-K20 (Methyl 2) Antibody Blocking Peptide - Product info

Primary AccessionP62805
Clone Names80928002
Calculated MW11367 Da

hH4-K20 (Methyl 2) Antibody Blocking Peptide - Additional info

Gene ID 8370
Target/Specificity
The synthetic peptide sequence used to generate the antibody AP3674a was selected from the Methyl region of human hH4-K20 (Methyl 2). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.

hH4-K20 (Methyl 2) Antibody Blocking Peptide - Protein Information

Name HIST1H4A
Synonyms H4/A, H4FA
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Cellular Location
Nucleus. Chromosome.

hH4-K20 (Methyl 2) Antibody Blocking Peptide - Related products

AP3655a: H4 Antibody ( K20[Me1] )

AP3657a: H4 Antibody ( K20[Me3] )

AP3674a: H4 Antibody ( K20 [Me2] )

AP5660a: H4-K20 Antibody (N-term)

RI12488: HIST2H4B predesign siRNA

BP3655a: hH4-K20[Me1] Blocking Peptide

BP3656a: hH4-K20[Me1] Blocking Peptide

BP3657a: hH4-K20[Me3] Blocking Peptide

BP3674a: hH4-K20 (Methyl 2) Antibody Blocking Peptide

AJ1360a: Histone-H4 Antibody Acetyl (K5)

AJ1360b: Histone-H4 Antibody Acetyl (K8)

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3/H4 tetramer and two H2A/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones.