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hH4-K20 (Methyl 2) Antibody Blocking PeptideSynthetic peptide
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| BP3674a | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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hH4-K20 (Methyl 2) Antibody Blocking Peptide - Product info | |
| Primary Accession | P62805 |
| Clone Names | 80928002 |
| Calculated MW | 11367 Da |
hH4-K20 (Methyl 2) Antibody Blocking Peptide - Additional info | |
| Gene ID 8370 | |
| Target/Specificity The synthetic peptide sequence used to generate the antibody AP3674a was selected from the Methyl region of human hH4-K20 (Methyl 2). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
hH4-K20 (Methyl 2) Antibody Blocking Peptide - Protein Information | |
| Name HIST1H4A | |
| Synonyms H4/A, H4FA | |
| Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling | |
| Cellular Location Nucleus. Chromosome. | |
hH4-K20 (Methyl 2) Antibody Blocking Peptide - Related products
AP3655a: H4 Antibody ( K20[Me1] )
AP3657a: H4 Antibody ( K20[Me3] )
AP3674a: H4 Antibody ( K20 [Me2] )
AP5660a: H4-K20 Antibody (N-term)
RI12488: HIST2H4B predesign siRNA
BP3655a: hH4-K20[Me1] Blocking Peptide
BP3656a: hH4-K20[Me1] Blocking Peptide
BP3657a: hH4-K20[Me3] Blocking Peptide
BP3674a: hH4-K20 (Methyl 2) Antibody Blocking Peptide
hH4-K20 (Methyl 2) Antibody Blocking Peptide - Research Areas
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BACKGROUND
Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3/H4 tetramer and two H2A/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones.