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Phospho-IRS1(Y989) Antibody Blocking peptide

Synthetic peptide

     
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Primary Accession P35568
Peptide ID 27012
Additional Information
Gene ID 3667
Other Names Insulin receptor substrate 1, IRS-1, IRS1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name IRS1
Function May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
Research Areas
Citations (0)

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Background

IRS1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor it binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. It activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.

References

Kawakami,A., Circulation 118 (7), 731-742 (2008)Yi,Z., Anal. Chem. 77 (17), 5693-5699 (2005)

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$ 80.00
Cat# BP3704a
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