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Phospho-PUM2-S182 Antibody Blocking PeptideSynthetic peptide

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United States
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Ordering Information
Catalog # Size Availability Price  
BP3721a 0.1 mg 400 ul In Stock $ 45.00 Add to cart
  • Specification
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Phospho-PUM2-S182 Antibody Blocking Peptide - Product info

Primary AccessionQ8TB72
Calculated MW114216 Da

Phospho-PUM2-S182 Antibody Blocking Peptide - Additional info

Gene ID 23369
Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Phospho-PUM2-S182 Antibody Blocking Peptide - Protein Information

Name PUM2
Synonyms KIAA0235, PUMH2
Function
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts
Cellular Location
Cytoplasm (Probable). Cytoplasmic granule (By similarity). Cytoplasm, perinuclear region. Note=The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Co-localizes with NANOS3 in the stress granules (By similarity). Co-localizes with NANOS1 and SNAPIN in the perinuclear region of germ cells
Tissue Location
Expressed in male germ cells of adult testis (at protein level). Highly expressed in testis and ovary Predominantly expressed in stem cells and germ cells. Expressed at lower level in brain, heart, kidney, liver, muscle, placenta, intestine and stomach Expressed in cerebellum, corpus callosum, caudate nucleus, hippocampus, medulla oblongata and putamen Expressed in all fetal tissues tested

Phospho-PUM2-S182 Antibody Blocking Peptide - Related products

AP3721a: Phospho-PUM2- S182 Antibody

AP3733a: Phospho-PUM2- S136 Antibody

AP5827a: PUM2-S136 Antibody

AP7569b: PUM2 Antibody (N-term)

AP7734d: PUM2 Antibody (S182)

RI14366: PUM2 predesign siRNA

BP3721a: Phospho-PUM2-S182 Antibody Blocking Peptide

BP3733a: Phospho-PUM2-S136 Antibody Blocking peptide

BP5827a: PUM2-S136 Antibody Blocking peptide

BP7734d: PUM2 Antibody (S182) Blocking Peptide

AJ1420b: ISG15 Antibody

AJ1668a: Pumilio-2 Antibody

AF1886a: PUM2 Antibody

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

PUM2 is sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. It is interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.

REFERENCES

Ginter-Matuszewska, B., et al. Mol. Hum. Reprod. 15(3):173-179(2009)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Kusz, K., et al. Mol. Reprod. Dev. 74(6):795-799(2007)