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Phospho-PUM2-S182 Antibody Blocking PeptideSynthetic peptide
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| BP3721a | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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Phospho-PUM2-S182 Antibody Blocking Peptide - Product info | |
| Primary Accession | Q8TB72 |
| Calculated MW | 114216 Da |
Phospho-PUM2-S182 Antibody Blocking Peptide - Additional info | |
| Gene ID 23369 | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
Phospho-PUM2-S182 Antibody Blocking Peptide - Protein Information | |
| Name PUM2 | |
| Synonyms KIAA0235, PUMH2 | |
| Function Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts | |
| Cellular Location Cytoplasm (Probable). Cytoplasmic granule (By similarity). Cytoplasm, perinuclear region. Note=The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Co-localizes with NANOS3 in the stress granules (By similarity). Co-localizes with NANOS1 and SNAPIN in the perinuclear region of germ cells | |
| Tissue Location Expressed in male germ cells of adult testis (at protein level). Highly expressed in testis and ovary Predominantly expressed in stem cells and germ cells. Expressed at lower level in brain, heart, kidney, liver, muscle, placenta, intestine and stomach Expressed in cerebellum, corpus callosum, caudate nucleus, hippocampus, medulla oblongata and putamen Expressed in all fetal tissues tested | |
Phospho-PUM2-S182 Antibody Blocking Peptide - Related products
AP3721a: Phospho-PUM2- S182 Antibody
AP3733a: Phospho-PUM2- S136 Antibody
AP7569b: PUM2 Antibody (N-term)
BP3721a: Phospho-PUM2-S182 Antibody Blocking Peptide
BP3733a: Phospho-PUM2-S136 Antibody Blocking peptide
BP5827a: PUM2-S136 Antibody Blocking peptide
Phospho-PUM2-S182 Antibody Blocking Peptide - Research Areas
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BACKGROUND
PUM2 is sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. It is interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.
REFERENCES
Ginter-Matuszewska, B., et al. Mol. Hum. Reprod. 15(3):173-179(2009)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Kusz, K., et al. Mol. Reprod. Dev. 74(6):795-799(2007)