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Phospho-GATA6(Y271) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q92908
Other Accession NP_005248.2
Additional Information
Gene ID 2627
Other Names GATA6; Transcription factor GATA-6; GATA-binding factor 6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GATA6
Function Transcriptional activator that regulates SEMA3C and PLXNA2. Thought to be important for regulating terminal differentiation and/or proliferation. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity).
Cellular Location Nucleus.
Tissue Location Expressed in heart, gut and gut-derived tissues
Research Areas
Citations (0)

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Thought to be important for regulating terminal differentiation and/or proliferation.


References for protein:
1.Artus, J., et al. Development 137(20):3361-3372(2010)
2.Lin, X., et al. J. Hum. Genet. 55(10):662-667(2010)
3.Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
4.Thye, T., et al. Nat. Genet. 42(9):739-741(2010)
5.Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010)
References for HepG2 cell line:
1. Knowles BB, et al. (1980). Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science 209: 497-499.[ PubMed: 6248960].
2. Darlington GJ, et al. (1987). Growth and hepatospecific gene expression of human hepatoma cells in a defined medium. In Vitro Cell. Dev. Biol. 23: 349-354.[PubMed: 3034851].
3. Ihrke, G; Neufeld, EB; Meads, T; Shanks, MR; Cassio, D; Laurent, M; Schroer, TA; Pagano, RE et al. (1993). "WIF-B cells: an in vitro model for studies of hepatocyte polarity". Journal of Cell Biology 123 (6): 1761–1775. [PubMed:7506266].
4. Mersch-Sundermann, V.; Knasmüller, S.; Wu, X. J.; Darroudi, F.; Kassie, F. (2004). "Use of a human-derived liver cell line for the detection of cytoprotective, antigenotoxic and cogenotoxic agents". Toxicology 198 (1–3): 329–340. [PubMed:15138059].

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$ 80.00
$ 99.00
Cat# BP3766a
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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