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Phospho-mouse BAD(S134) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q61337
Other Accession O35147, NP_031548.1
Additional Information
Gene ID 12015
Other Names Bcl2-associated agonist of cell death, BAD, Bcl-2-binding component 6, Bcl-xL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death, Bad, Bbc6
Target/Specificity The synthetic peptide sequence is selected from aa 127-141 of MOUSE Bad
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Bad
Synonyms Bbc6
Function Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Cellular Location Mitochondrion outer membrane. Cytoplasm. Note=Colocalizes with HIF3A isoform 2 in the cytoplasm (PubMed:21546903). Upon phosphorylation, locates to the cytoplasm.
Research Areas
Citations (0)

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Bad may be involved in induction of programmed cell death [RGD].


Santidrian, A.F., et al. Blood 116(16):3023-3032(2010)
Frenzel, A., et al. Blood 115(5):995-1005(2010)
Quoyer, J., et al. J. Biol. Chem. 285(3):1989-2002(2010)
Polzien, L., et al. J. Biol. Chem. 284(41):28004-28020(2009)
Wu, X., et al. Diabetologia 52(10):2130-2141(2009)

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$ 80.00
$ 99.00
Cat# BP3777o
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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