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Phospho-TJP2(S978) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UDY2
Other Accession NP_001164101.1
Additional Information
Gene ID 9414
Other Names Tight junction protein ZO-2, Tight junction protein 2, Zona occludens protein 2, Zonula occludens protein 2, TJP2, X104, ZO2
Target/Specificity The synthetic peptide sequence is selected from aa 971-985 of HUMAN TJP2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TJP2
Synonyms X104, ZO2
Function Plays a role in tight junctions and adherens junctions.
Cellular Location Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, tight junction. Nucleus. Note=Also nuclear under environmental stress conditions and in migratory endothelial cells and subconfluent epithelial cell cultures.
Tissue Location This protein is found in epithelial cell junctions. Isoform A1 is abundant in the heart and brain. Detected in brain and skeletal muscle. It is present almost exclusively in normal tissues. Isoform C1 is expressed at high level in the kidney, pancreas, heart and placenta. Not detected in brain and skeletal muscle. Found in normal as well as in most neoplastic tissues.
Research Areas
Citations (0)

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This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutation in this gene have been identified in patients with hypercholanemia. Alternate splicing results in multiple transcript variants.


Lechuga, S., et al. Exp. Cell Res. 316(19):3124-3139(2010)
Remue, E., et al. FEBS Lett. 584(19):4175-4180(2010)
Walsh, T., et al. Am. J. Hum. Genet. 87(1):101-109(2010)
Meerschaert, K., et al. Cell. Mol. Life Sci. 66(24):3951-3966(2009)
Fanning, A.S., et al. Ann. N. Y. Acad. Sci. 1165, 113-120 (2009) :

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$ 80.00
$ 99.00
Cat# BP3790a
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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