|Other Names||Protein transport protein Sec24A, SEC24-related protein A, SEC24A|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.|
|Cellular Location||Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum membrane. Golgi apparatus membrane|
|Tissue Location||Expressed in fibroblasts, hepatocytes, and lymphocytes|
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Provided below are standard protocols that you may find useful for product applications.
SC24A is a component of coat protein II (COPII; see MIM 601924)-coated vesicles that mediate protein transport from the endoplasmic reticulum. SEC24A is 1 of several mammalian proteins that show structural and functional homology to yeast Sec24.
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Mancias, J.D., et al. Mol. Cell 26(3):403-414(2007)Wendeler, M.W., et al. EMBO Rep. 8(3):258-264(2007)
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