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ADCL1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q6PIU2
Peptide ID 91119003
Additional Information
Gene ID 57552
Other Names Neutral cholesterol ester hydrolase 1, NCEH, 311-, Arylacetamide deacetylase-like 1, NCEH1, AADACL1, KIAA1363
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NCEH1
Synonyms AADACL1, KIAA1363
Function Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration.
Cellular Location Membrane; Single-pass type II membrane protein. Microsome
Tissue Location Expressed in monocyte-derived macrophages. Up- regulated in invasive melanoma and breast carcinoma cell lines
Research Areas
Citations (0)

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Background

ADCL1 hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. ADCL1 may be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also ADCL1 involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. ADCL1 may contribute to cancer pathogenesis by promoting tumor cell migration.

References

Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)Okazaki, H., et al. J. Biol. Chem. 283(48):33357-33364(2008)Chiang, K.P., et al. Chem. Biol. 13(10):1041-1050(2006)

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$ 80.00
Cat# BP4743a
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