NUP37 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8NFH4 |
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Gene ID | 79023 |
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Other Names | Nucleoporin Nup37, p37, Nup107-160 subcomplex subunit Nup37, NUP37 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | NUP37 |
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Function | Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. |
Cellular Location | Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex |
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Provided below are standard protocols that you may find useful for product applications.
Background
NPCs are composed of subcomplexes, and NUP37 is part of one such subcomplex, Nup107-160.
References
Kim, J.J., et al. J. Hum. Genet. 55(1):27-31(2010)Zuccolo, M., et al. EMBO J. 26(7):1853-1864(2007)Glavy, J.S., et al. Proc. Natl. Acad. Sci. U.S.A. 104(10):3811-3816(2007)
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