|Other Names||Partitioning defective 6 homolog gamma, PAR-6 gamma, PAR6D, PARD6G, PAR6G|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP- bound Rho small GTPases to atypical protein kinase C proteins (By similarity).|
|Cellular Location||Cytoplasm. Cell membrane. Cell junction, tight junction|
|Tissue Location||Widely expressed, with a higher expression in fetal and adult kidney|
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PAR6G involved in asymmetrical cell division and cell polarization processes. PAR6G may play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Brajenovic, M., et al. J. Biol. Chem. 279(13):12804-12811(2004)Kohjima, M., et al. Biochem. Biophys. Res. Commun. 299(4):641-646(2002)Suzuki, A., et al. J. Cell Biol. 152(6):1183-1196(2001)
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