|Other Names||Shadow of prion protein, Protein shadoo, SPRN, SHO|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP (By similarity).|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor|
|Tissue Location||Mainly expressed in brain. In brain, it is expressed in hippocampus.|
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Provided below are standard protocols that you may find useful for product applications.
SPRN has PrP(C)-like neuroprotective activity. SPRN may act as a modulator for the biological actions of normal and abnormal PrP.
Beck, J.A., et al. J. Med. Genet. 45(12):813-817(2008)Van den Brulle, J., et al. BioTechniques 45(3):340-343(2008)Premzl, M., et al. Mol. Biol. Evol. 21(12):2210-2231(2004)
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