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CQ068 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q2NKJ3
Peptide ID 91119136
Additional Information
Gene ID 80169
Other Names CST complex subunit CTC1, Conserved telomere maintenance component 1, HBV DNAPTP1-transactivated protein B, CTC1, C17orf68
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CTC1
Synonyms C17orf68
Function Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
Cellular Location Nucleus. Chromosome, telomere. Note=A transmembrane region is predicted by sequence analysis tools (ESKW, MEMSAT and Phobius); however, given the telomeric localization of the protein, the relevance of the transmembrane region is unsure in vivo
Research Areas
Citations (0)

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CQ068 is subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication. CQ068 also appears to function in a telomere-associated complex with OBFC1 and TEN1.


Surovtseva, Y.V., et al. Mol. Cell 36(2):207-218(2009)Miyake, Y., et al. Mol. Cell 36(2):193-206(2009)Casteel, D.E., et al. J. Biol. Chem. 284(9):5807-5818(2009)

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$ 80.00
Cat# BP4761c
(40 western blots)
Availability: In Stock
Bulk Size
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