|Other Names||Popeye domain-containing protein 2, Popeye protein 2, POPDC2, POP2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density.|
|Cellular Location||Membrane; Multi-pass membrane protein. Cell membrane, sarcolemma|
|Tissue Location||Expressed predominantly in the heart and in the skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
POPDC2 encodes a member of the POP family of proteins which contain three putative transmembrane domains. This membrane associated protein is predominantly expressed in skeletal and cardiac muscle, and may have an important function in these tissues.
Andree, B., et al. Dev. Biol. 223(2):371-382(2000)
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