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ZNF9 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P62633 |
|---|
| Gene ID | 7555 |
|---|---|
| Other Names | Cellular nucleic acid-binding protein, CNBP, Zinc finger protein 9, CNBP, RNF163, ZNF9 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CNBP (HGNC:13164) |
|---|---|
| Synonyms | RNF163, ZNF9 |
| Function | Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression (PubMed:2562787). Has a role as transactivator of the Myc promoter (By similarity). Binds single-stranded RNA in a sequence-specific manner (By similarity). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:P53996}. Cytoplasm. Endoplasmic reticulum {ECO:0000250|UniProtKB:P53996} [Isoform 2]: Cytoplasm [Isoform 5]: Cytoplasm [Isoform 8]: Cytoplasm |
| Tissue Location | Expressed in the liver, kidney, spleen, testis, lung, muscle and adrenal glands. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZNF9 encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2.
References
Lucchiari, S., et al. J. Neurol. Sci. 275 (1-2), 159-163 (2008) Auvinen, S., et al. Arthritis Rheum. 58(11):3627-3631(2008)Gerbasi, V.R., et al. Mol. Cell Proteomics 6(6):1049-1058(2007)Toth, C., et al. Muscle Nerve 35(2):259-264(2007)
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