B3GNT7 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8NFL0 |
---|
Gene ID | 93010 |
---|---|
Other Names | UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 7, BGnT-7, Beta-1, 3-Gn-T7, Beta-1, 3-N-acetylglucosaminyltransferase 7, Beta3Gn-T7, 241-, B3GNT7 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | B3GNT7 {ECO:0000303|PubMed:17690104, ECO:0000312|HGNC:HGNC:18811} |
---|---|
Function | N-acetyl glucosamine (GlcNAc) transferase that catalyzes the transfer of GlcNAc via a beta1->3 linkage from UDP-GlcNAc to the non- reducing terminal galactose (Gal) in the linearly growing chain of N- and O-linked keratan sulfate proteoglycans. Cooperates with B4GALT4 galactosyltransferase and CHST6 and CHST1 sulfotransferases to construct and elongate mono- and disulfated disaccharide units [->3Galbeta1->4(6-sulfoGlcNAcbeta)1->] and [->3(6-sulfoGalbeta)1->4(6- sulfoGlcNAcbeta)1->] within keratan sulfate polymer (PubMed:14706853, PubMed:17690104). Involved in biosynthesis of N-linked keratan sulfate proteoglycans in cornea, with an impact on proteoglycan fibril organization and corneal transparency (PubMed:17690104) (By similarity). May play a role in the maintenance of tissue architecture by suppressing cellular motility and invasion (By similarity). |
Cellular Location | Golgi apparatus membrane; Single- pass type II membrane protein |
Tissue Location | Expressed in corneal epithelial cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
B3GNT7 is a glycosyltransferase which may play a role in elongation of the keratan sulfate carbohydrate backbone.
References
Kitayama, K., et al. J. Biol. Chem. 282(41):30085-30096(2007)Seko, A., et al. FEBS Lett. 556 (1-3), 216-220 (2004) Kataoka, K., et al. Biochem. Biophys. Res. Commun. 294(4):843-848(2002)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.