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RPS15A Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P62244
Additional Information
Gene ID 6210
Other Names 40S ribosomal protein S15a, RPS15A
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RPS15A (HGNC:10389)
Function Component of the small ribosomal subunit (PubMed:23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre- ribosomal RNA by the RNA exosome (PubMed:34516797). Required for proper erythropoiesis (PubMed:27909223).
Cellular Location Cytoplasm. Nucleus, nucleolus
Research Areas
Citations (0)
citation

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Background

RPS15A consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

References

Yu, Y., et al. Protein Sci. 14(6):1438-1446(2005)Lian, Z., et al. Mol. Carcinog. 40(1):34-46(2004)Lehner, B., et al. Genomics 83(1):153-167(2004)

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$ 277.78
Cat# BP4804a
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