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SF3B14 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9Y3B4
Peptide ID 37541
Additional Information
Gene ID 51639
Other Names Splicing factor 3B subunit 6, Pre-mRNA branch site protein p14, SF3b 14 kDa subunit, SF3B14a, Spliceosome-associated protein, 14-kDa, Splicing factor 3b, subunit 6, 14kDa, SF3B6, SAP14, SF3B14, SF3B14A
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SF3B6
Synonyms SAP14, SF3B14, SF3B14A
Function Necessary for the splicing of pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively.
Cellular Location Nucleus.
Research Areas
Citations (0)

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SF3B14 encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.


Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) Schellenberg, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 103(5):1266-1271(2006)

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$ 80.00
Cat# BP4807b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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