|Other Names||Decaprenyl-diphosphate synthase subunit 2, All-trans-decaprenyl-diphosphate synthase subunit 2, Candidate tumor suppressor protein, Decaprenyl pyrophosphate synthase subunit 2, PDSS2, C6orf210, DLP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10.|
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Provided below are standard protocols that you may find useful for product applications.
DLP1 is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.
Chen, P., et al. Anticancer Drugs 20(2):141-148(2009)Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)Diomedi-Camassei, F., et al. J. Am. Soc. Nephrol. 18(10):2773-2780(2007)
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