|Other Names||Threonine synthase-like 2, TSH2, 423-, Secreted osteoclastogenic factor of activated T-cells, SOFAT, THNSL2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Isoform 1: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho- threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity).|
|Cellular Location||Isoform SOFAT: Secreted. Note=Secreted by activated T-cells via a calcineurin-independent pathway|
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Provided below are standard protocols that you may find useful for product applications.
THNS2 acts as a catabolic phospho-lyase on both gamma-and beta-phosphorylated substrates. THNS2 degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate.
Donini, S., et al. Biochem. Biophys. Res. Commun. 350(4):922-928(2006)Hallikas, O., et al. Cell 124(1):47-59(2006)
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