|Other Names||Selenocysteine-specific elongation factor, Elongation factor sec, Eukaryotic elongation factor, selenocysteine-tRNA-specific, EEFSEC, SELB|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.|
|Cellular Location||Cytoplasm. Nucleus|
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Provided below are standard protocols that you may find useful for product applications.
EEFSEC is translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.
Gudmundsson, J., et al. Nat. Genet. 41(10):1122-1126(2009)Donovan, J., et al. J. Biol. Chem. 283(50):35129-35139(2008)Muzny, D.M., et al. Nature 440(7088):1194-1198(2006)
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