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CCR1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P32246
Peptide ID 44176
Additional Information
Gene ID 1230
Other Names C-C chemokine receptor type 1, C-C CKR-1, CC-CKR-1, CCR-1, CCR1, HM145, LD78 receptor, Macrophage inflammatory protein 1-alpha receptor, MIP-1alpha-R, RANTES-R, CD191, CCR1, CMKBR1, CMKR1, SCYAR1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCR1
Synonyms CMKBR1, CMKR1, SCYAR1
Function Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1- beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Widely expressed in different hematopoietic cells
Research Areas
Citations (0)

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CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.


Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)Anderson, M.W., et al. Am. J. Clin. Pathol. 133(3):473-483(2010)Amundsen, S.S., et al. Genes Immun. 11(1):79-86(2010)

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$ 80.00
Cat# BP4859a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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