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DDX23 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9BUQ8
Peptide ID 90921091
Additional Information
Gene ID 9416
Other Names Probable ATP-dependent RNA helicase DDX23, 100 kDa U5 snRNP-specific protein, DEAD box protein 23, PRP28 homolog, U5-100kD, DDX23
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DDX23
Function Involved in pre-mRNA splicing and its phosphorylated form (by SRPK2) is required for spliceosomal B complex formation.
Cellular Location Nucleus
Research Areas
Citations (0)

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Background

DDX23 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing.

References

Mathew, R., et al. Nat. Struct. Mol. Biol. 15(5):435-443(2008)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 80.00
Cat# BP4866c
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