|Other Names||Thioredoxin domain-containing protein 12, Endoplasmic reticulum resident protein 18, ER protein 18, ERp18, Endoplasmic reticulum resident protein 19, ER protein 19, ERp19, Thioredoxin-like protein p19, hTLP19, TXNDC12, TLP19|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Possesses significant protein thiol-disulfide oxidase activity.|
|Cellular Location||Endoplasmic reticulum lumen|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
TXNDC12 belongs to the thioredoxin superfamily (see TXN; MIM 187700). Members of this superfamily possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors
Jessop, C.E., et al. J. Cell. Sci. 122 (PT 23), 4287-4295 (2009) Rowe, M.L., et al. Biochemistry 48(21):4596-4606(2009)Jeong, W., et al. J. Biol. Chem. 283(37):25557-25566(2008)
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