|Other Names||Guanine nucleotide-binding protein G(t) subunit alpha-2, Transducin alpha-2 chain, GNAT2, GNATC|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.|
|Tissue Location||Retinal rod outer segment.|
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Provided below are standard protocols that you may find useful for product applications.
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones.
Thiadens, A.A., et al. Ophthalmology 116(10):1984-1989(2009)Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)Oldham, W.M., et al. Nat. Struct. Mol. Biol. 13(9):772-777(2006)Rosenberg, T., et al. Invest. Ophthalmol. Vis. Sci. 45(12):4256-4262(2004)
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