IMPG1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q17R60 |
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Gene ID | 3617 |
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Other Names | Interphotoreceptor matrix proteoglycan 1, Interphotoreceptor matrix proteoglycan of 150 kDa, IPM-150, Sialoprotein associated with cones and rods, IMPG1 {ECO:0000312|EMBL:AAI174531} |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | IMPG1 {ECO:0000312|EMBL:AAI17453.1} |
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Function | Chondroitin sulfate-, heparin- and hyaluronan-binding protein (By similarity). May serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix (PubMed:9813076). |
Cellular Location | Cell projection, cilium, photoreceptor outer segment. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix. Photoreceptor inner segment {ECO:0000250|UniProtKB:Q8R1W8} |
Tissue Location | Expressed in the retina (at protein level) (PubMed:10601738, PubMed:29777959). In the retina, specifically expressed by cone and rod photoreceptor cells (PubMed:9813076) Localizes to cone and rod photoreceptor cells surrounding the interphotoreceptor matrix of the retina (PubMed:9719680) |
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Provided below are standard protocols that you may find useful for product applications.
Background
IMPG1 may interact with hyaluronan which may serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix.
References
Abd El-Aziz, M.M., et al. Curr. Eye Res. 30(12):1081-1087(2005)van Lith-Verhoeven, J.J., et al. Invest. Ophthalmol. Vis. Sci. 45(1):30-35(2004)Mungall, A.J., et al. Nature 425(6960):805-811(2003)
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