|Other Names||Guanylate-binding protein 7, GTP-binding protein 7, GBP-7, Guanine nucleotide-binding protein 7, Guanylate-binding protein 4-like, GBP7, GBP4L|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Guanylate-binding proteins, such as GBP7, are induced by interferon and hydrolyze GTP to both GDP and GMP.
Olszewski, M.A., et al. J. Interferon Cytokine Res. 26(5):328-352(2006)
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