PLA2G4B Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P0C869 |
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Gene ID | 100137049;8681 |
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Other Names | Cytosolic phospholipase A2 beta, cPLA2-beta, Phospholipase A2 group IVB, PLA2G4B |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PLA2G4B |
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Function | Calcium-dependent phospholipase A1 and A2 and lysophospholipase that may play a role in membrane phospholipid remodeling. |
Cellular Location | [Isoform 3]: Cytoplasm, cytosol. Mitochondrion membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein. Note=Translocates to membrane vesicles in a calcium-dependent fashion. |
Tissue Location | Widely expressed. Expressed at higher level in brain, heart, liver, cerebellum and pancreas |
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Provided below are standard protocols that you may find useful for product applications.
Background
PLA2G4B transcribes naturally-occurring mRNAs that are co-transcribed products of the neighboring JMJD7 and PLA2G4B genes. Incompletely processed read-through transcripts from these two loci are abundantly expressed in most tissues, but the function of the predicted protein product has not yet been determined.
References
Ghosh, M., et al. J. Biol. Chem. 281(24):16615-16624(2006)Tao, R., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 137B (1), 56-58 (2005) Pope, S.N., et al. J. Steroid Biochem. Mol. Biol. 94 (1-3), 203-208 (2005)
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