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CSGALNACT1 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8TDX6
Peptide ID 90921038
Additional Information
Gene ID 55790
Other Names Chondroitin sulfate N-acetylgalactosaminyltransferase 1, CsGalNAcT-1, Chondroitin beta-1, 4-N-acetylgalactosaminyltransferase 1, Beta4GalNAcT-1, CSGALNACT1, CHGN, GALNACT1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSGALNACT1
Synonyms CHGN, GALNACT1
Function Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage.
Cellular Location Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein
Tissue Location Ubiquitous, with the highest levels in placenta, thyroid, bladder, prostate and adrenal gland. Detected at low levels in the other tissues examined
Research Areas
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Background

CSGALNACT1 transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). CSGALNACT1 required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. CSGALNACT1 is important role in chondroitin chain biosynthesis in cartilage.

References

Landa, I., et al. PLoS Genet. 5 (9), E1000637 (2009) Sakai, K., et al. J. Biol. Chem. 282(6):4152-4161(2007)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)

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$ 80.00
Cat# BP4922c
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