|Other Names||High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I, Fc-gamma RI, FcRI, Fc-gamma RIA, FcgammaRIa, CD64, FCGR1A, FCG1, FCGR1, IGFR1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||FCG1, FCGR1, IGFR1|
|Function||High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein Note=Stabilized at the cell membrane through interaction with FCER1G|
|Tissue Location||Monocyte/macrophage specific.|
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Provided below are standard protocols that you may find useful for product applications.
FCGR1A encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
Poon, I.K., et al. Blood 115(12):2473-2482(2010)Jung, S.T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(2):604-609(2010)Hulse, K.E., et al. J. Allergy Clin. Immunol. 125(1):247-256(2010)
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