|Other Names||Putative pregnancy-specific beta-1-glycoprotein 7, PS-beta-G-7, PSBG-7, Pregnancy-specific glycoprotein 7, PSG7|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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PSG7 is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The reference genome contains a nonsense mutation that disrupts the coding sequence, suggesting that this gene may be evolving into a pseudogene.
Grimwood, J., et al. Nature 428(6982):529-535(2004)Beauchemin, N., et al. Exp. Cell Res. 252(2):243-249(1999)Adams, M.D., et al. Nature 377 (6547 SUPPL), 3-174 (1995)
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