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T131L Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | A2VDJ0 |
|---|---|
| Other Accession | NP_056011 |
| Gene ID | 23240 |
|---|---|
| Other Names | Transmembrane protein 131-like, KIAA0922, TMEM131L |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TMEM131L (HGNC:29146) |
|---|---|
| Function | [Isoform 1]: Membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte proliferation. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=During intrathymic development, resides in punctate cytoplasmic structures in DN1 and DN2 cells. In DN3 cells, found in large crescent-shaped membrane structures, which preferentially localize in cell-to-cell contact zones [Isoform 5]: Cytoplasm. Note=Scattered throughout the cytoplasm in small-sized punctate structures. |
| Tissue Location | Expressed in thymocytes. |
Research Areas
Citations (0)
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Application Protocols
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$ 277.78
Cat# BP4964b
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