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RAB27B Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O00194 |
|---|---|
| Other Accession | NP_004154 |
| Gene ID | 5874 |
|---|---|
| Other Names | Ras-related protein Rab-27B, C25KG, RAB27B |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RAB27B |
|---|---|
| Function | Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381). Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (PubMed:21775604). May be involved in targeting uroplakins to urothelial apical membranes (By similarity). |
| Cellular Location | Membrane; Lipid-anchor. Late endosome |
| Tissue Location | Expressed primarily in testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
RAB27B may be involved in targeting uroplakins to urothelial apical membranes.
References
Hayasaka, S., et al. Asian J. Androl. 10(4):561-568(2008)Shirakawa, R., et al. J. Biol. Chem. 279(11):10730-10737(2004)Tiwari, S., et al. Blood 102(12):3970-3979(2003)
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