TPPP3 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9BW30 |
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Gene ID | 51673 |
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Other Names | Tubulin polymerization-promoting protein family member 3, TPPP/p20, TPPP3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TPPP3 {ECO:0000303|PubMed:19633818, ECO:0000312|HGNC:HGNC:24162} |
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Function | Regulator of microtubule dynamic that has microtubule bundling activity (PubMed:17105200, PubMed:19633818). Required for embryo implantation; possibly by regulating beta-catenin (By similarity). Also required for decidualization via regulation of beta- catenin (PubMed:30667362). |
Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton |
Tissue Location | Expressed in endometrium during the mid-secretory phase (LH + 7) (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
TPPP3 binds tubulin and has microtubule bundling activity. TPPP3 may play a role in cell proliferation and mitosis.
References
Zhou, W., et al. Mol. Cell. Biochem. 333 (1-2), 91-98 (2010) Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)Vincze, O., et al. Biochemistry 45(46):13818-13826(2006)
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