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CD80 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P33681 |
|---|
| Gene ID | 941 |
|---|---|
| Other Names | T-lymphocyte activation antigen CD80, Activation B7-1 antigen, BB1, CTLA-4 counter-receptor B71, B7, CD80, CD80, CD28LG, CD28LG1, LAB7 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CD80 |
|---|---|
| Synonyms | CD28LG, CD28LG1, LAB7 |
| Function | Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Location | Expressed on activated B-cells, macrophages and dendritic cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
CD80 is activation antigen B7-1 (formerly referred to as B7) provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 (MIM 186760) and CTLA4 (MIM 123890) ligands of T cells.
References
Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)Segat, L., et al. J. Gastroenterol. Hepatol. 24(12):1840-1846(2009)
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