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GALP Antibody (C-term) Blocking PeptideSynthetic peptide

Country
United States
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Ordering Information
Catalog # Size Availability Price  
BP5033b 0.1 mg 400 ul In Stock $ 45.00 Add to cart
  • Specification
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GALP Antibody (C-term) Blocking Peptide - Product info

Primary AccessionQ9UBC7
Calculated MW12545 Da

GALP Antibody (C-term) Blocking Peptide - Additional info

Gene ID 85569
Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.

GALP Antibody (C-term) Blocking Peptide - Protein Information

Name GALP
Function
Hypothalamic neuropeptide which binds to the G-protein- coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin- releasing hormone secretion. Isoform 2 exhibits potent and dose- dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effects which does not appear to be mediated via GALR1 or GALR2 (By similarity)
Cellular Location
Secreted.
Tissue Location
Isoform 2 is found in ganglia of ganglioneuroma and ganglioneuroblastoma, as well as in differentiated tumor cells of neuroblastoma tissues. Not found in undifferentiated neuroblasts. Isoform 2 is found in the skin, in pericytes covering microvascular arterioles and venules on their abluminal surfaces. In larger vessels, isoform 2 is expressed in layers of smooth muscle cells. Isoform 2 is not detected in endothelial cells

GALP Antibody (C-term) Blocking Peptide - Related products

AP5033b: GALP Antibody (C-term)

BP5033b: GALP Antibody (C-term) Blocking Peptide

GALP Antibody (C-term) Blocking Peptide - Research Areas

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

GALP encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction.

REFERENCES

Schjeide, B.M., et al. Neurogenetics 10(1):19-25(2009)Lang, R., et al. Pharmacol. Ther. 115(2):177-207(2007)Santic, R., et al. Proc. Natl. Acad. Sci. U.S.A. 104(24):10217-10222(2007)