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GALP Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9UBC7
Additional Information
Gene ID 85569
Other Names Galanin-like peptide, GALP
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GALP
Function [Isoform 1]: Hypothalamic neuropeptide which binds to the G- protein-coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion.
Cellular Location Secreted.
Tissue Location Isoform 2 is found in ganglia of ganglioneuroma and ganglioneuroblastoma, as well as in differentiated tumor cells of neuroblastoma tissues. Not found in undifferentiated neuroblasts Isoform 2 is found in the skin, in pericytes covering microvascular arterioles and venules on their abluminal surfaces. In larger vessels, isoform 2 is expressed in layers of smooth muscle cells. Isoform 2 is not detected in endothelial cells
Research Areas
Citations (0)
citation

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Background

GALP encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction.

References

Schjeide, B.M., et al. Neurogenetics 10(1):19-25(2009)Lang, R., et al. Pharmacol. Ther. 115(2):177-207(2007)Santic, R., et al. Proc. Natl. Acad. Sci. U.S.A. 104(24):10217-10222(2007)

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$ 277.78
Cat# BP5033b
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