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GALP Antibody (C-term) Blocking PeptideSynthetic peptide
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| BP5033b | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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GALP Antibody (C-term) Blocking Peptide - Product info | |
| Primary Accession | Q9UBC7 |
| Calculated MW | 12545 Da |
GALP Antibody (C-term) Blocking Peptide - Additional info | |
| Gene ID 85569 | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
GALP Antibody (C-term) Blocking Peptide - Protein Information | |
| Name GALP | |
| Function Hypothalamic neuropeptide which binds to the G-protein- coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin- releasing hormone secretion. Isoform 2 exhibits potent and dose- dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effects which does not appear to be mediated via GALR1 or GALR2 (By similarity) | |
| Cellular Location Secreted. | |
| Tissue Location Isoform 2 is found in ganglia of ganglioneuroma and ganglioneuroblastoma, as well as in differentiated tumor cells of neuroblastoma tissues. Not found in undifferentiated neuroblasts. Isoform 2 is found in the skin, in pericytes covering microvascular arterioles and venules on their abluminal surfaces. In larger vessels, isoform 2 is expressed in layers of smooth muscle cells. Isoform 2 is not detected in endothelial cells | |
GALP Antibody (C-term) Blocking Peptide - Related products
GALP Antibody (C-term) Blocking Peptide - Research Areas
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BACKGROUND
GALP encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction.
REFERENCES
Schjeide, B.M., et al. Neurogenetics 10(1):19-25(2009)Lang, R., et al. Pharmacol. Ther. 115(2):177-207(2007)Santic, R., et al. Proc. Natl. Acad. Sci. U.S.A. 104(24):10217-10222(2007)