PTS Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q03393 |
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Gene ID | 5805 |
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Other Names | 6-pyruvoyl tetrahydrobiopterin synthase, PTP synthase, PTPS, PTS |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PTS |
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Function | Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PTS catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity.
References
Schnetz-Boutaud, N.C., et al. Genes Brain Behav. 8(8):753-757(2009)Clot, F., et al. Brain 132 (PT 7), 1753-1763 (2009) Gu, M.Q., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 26(2):183-186(2009)
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