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TM127 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O75204
Peptide ID 91208094
Additional Information
Gene ID 55654
Other Names Transmembrane protein 127, TMEM127
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMEM127
Function Controls cell proliferation acting as a negative regulator of TOR signaling pathway mediated by mTORC1. May act as a tumor suppressor.
Cellular Location Cell membrane; Multi-pass membrane protein. Cytoplasm Note=Association of TMEM127 with the cell membrane is enhanced by inhibition of endocytosis. In the cytoplasm, it colocalizes with markers of early endosomal structures, Golgi apparatus and lysosomes.
Tissue Location Widely expressed.
Research Areas
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References

Qin, Y., et al. Nat. Genet. 42(3):229-233(2010)Hillier, L.W., et al. Nature 434(7034):724-731(2005)Loftus, B.J., et al. Genomics 60(3):295-308(1999)

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$ 80.00
Cat# BP5082a
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