|Other Names||Protein tweety homolog 3, hTTY3, TTYH3, KIAA1691|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in excitable tissues. Expressed in the brain, heart, skeletal muscle, colon, spleen, kidney and peripheral blood leukocytes.|
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Provided below are standard protocols that you may find useful for product applications.
TTYH3 encodes a member of the tweety family of proteins. TTYH3 is members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel.
He, Y., et al. J. Biol. Chem. 283(35):24000-24010(2008)Suzuki, M., et al. J. Biol. Chem. 279(21):22461-22468(2004)
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