|Other Names||Zinc-activated ligand-gated ion channel, Ligand-gated ion channel zinc-activated 1, Ligand-gated ion-channel receptor L2, ZACN, L2, LGICZ, LGICZ1, ZAC|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||L2, LGICZ, LGICZ1, ZAC|
|Function||Zinc-activated ligand-gated ion channel.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Detected in pancreas, brain, liver, placenta, trachea, kidney, spinal cord, stomach and fetal brain. In the adult brain region expression is detected in the hippocampus, striatum, amygdala and thalamus.|
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Provided below are standard protocols that you may find useful for product applications.
ZACN is a zinc-activated ligand-gated ion channel that defines a new subgroup of the cysteine-loop superfamily of ligand-gated ion channels.
Houtani, T., et al. Biochem. Biophys. Res. Commun. 335(2):277-285(2005)Davies, P.A., et al. J. Biol. Chem. 278(2):712-717(2003)
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