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G6PD Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P11413
Peptide ID 80703073
Additional Information
Gene ID 2539
Other Names Glucose-6-phosphate 1-dehydrogenase, G6PD, G6PD
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name G6PD
Function Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.
Tissue Location Isoform Long is found in lymphoblasts, granulocytes and sperm
Research Areas
Citations (0)

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Background

G6PD encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia.

References

Louicharoen, C., et al. Science 326(5959):1546-1549(2009)Zhong, D.N., et al. Zhongguo Dang Dai Er Ke Za Zhi 11(12):970-972(2009)Tiono, A.B., et al. Am. J. Trop. Med. Hyg. 81(6):969-978(2009)

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$ 80.00
Cat# BP5094c
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