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PARD6A Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NPB6
Peptide ID 90723098
Additional Information
Gene ID 50855
Other Names Partitioning defective 6 homolog alpha, PAR-6, PAR-6 alpha, PAR-6A, PAR6C, Tax interaction protein 40, TIP-40, PARD6A, PAR6A
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms PAR6A
Function Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Cellular Location Cytoplasm. Cell membrane. Cell projection, ruffle. Cell junction, tight junction. Note=Colocalizes with GTP- bound CDC42 or RAC1 at membrane ruffles and with PARD3 and PRKCI at epithelial tight junctions
Tissue Location Expressed in pancreas, skeletal muscle, brain and heart. Weakly expressed in kidney and placenta
Research Areas
Citations (0)

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PARD6A is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas.


Justilien, V., et al. Oncogene 28(41):3597-3607(2009)Viloria-Petit, A.M., et al. Proc. Natl. Acad. Sci. U.S.A. 106(33):14028-14033(2009)Narimatsu, M., et al. Cell 137(2):295-307(2009)

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$ 80.00
Cat# BP5107c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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