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C14orf100 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9P055 |
|---|
| Gene ID | 51528 |
|---|---|
| Other Names | JNK1/MAPK8-associated membrane protein, JKAMP, JNK1-associated membrane protein, JAMP, Medulloblastoma antigen MU-MB-504, JKAMP, C14orf100, JAMP |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | JKAMP |
|---|---|
| Synonyms | C14orf100, JAMP |
| Function | Regulates the duration of MAPK8 activity in response to various stress stimuli (By similarity). Facilitates degradation of misfolded endoplasmic reticulum (ER) proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system (PubMed:18784250). |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
C14orf100 may be a regulator of the duration of MAPK8 activity in response to various stress stimuli. C14orf100 facilitates degradation of misfolded endoplasmic reticulum (ER) luminal proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system.
References
Tcherpakov, M., et al. J. Biol. Chem. 284(18):12099-12109(2009)Tcherpakov, M., et al. Mol. Biol. Cell 19(11):5019-5028(2008)Kadoya, T., et al. Mol. Cell. Biol. 25(19):8619-8630(2005)
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