|Other Names||JNK1/MAPK8-associated membrane protein, JKAMP, JNK1-associated membrane protein, JAMP, Medulloblastoma antigen MU-MB-504, JKAMP, C14orf100, JAMP|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be a regulator of the duration of MAPK8 activity in response to various stress stimuli. Facilitates degradation of misfolded endoplasmic reticulum (ER) luminal proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system (By similarity).|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
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C14orf100 may be a regulator of the duration of MAPK8 activity in response to various stress stimuli. C14orf100 facilitates degradation of misfolded endoplasmic reticulum (ER) luminal proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system.
Tcherpakov, M., et al. J. Biol. Chem. 284(18):12099-12109(2009)Tcherpakov, M., et al. Mol. Biol. Cell 19(11):5019-5028(2008)Kadoya, T., et al. Mol. Cell. Biol. 25(19):8619-8630(2005)
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