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ZFYVE16 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q7Z3T8
Additional Information
Gene ID 9765
Other Names Zinc finger FYVE domain-containing protein 16, Endofin, Endosome-associated FYVE domain protein, ZFYVE16, KIAA0305
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZFYVE16
Synonyms KIAA0305
Function May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.
Cellular Location Cytoplasm. Early endosome membrane; Peripheral membrane protein. Note=Localized to early endosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate (PI3P)
Tissue Location Widely expressed. Highly expressed in kidney, placenta and lung. Expressed at intermediate level in heart, brain, skeletal muscle, spleen and liver. Weakly expressed in colon, thymus and peripheral blood lymphocytes.
Research Areas
Citations (0)
citation

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Background

The ZFYVE16 gene encodes endofin, an endosomal protein implicated in regulating membrane trafficking. It is characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain positioned in the middle of the molecule.

References

Toy, W., et al. Cell. Signal. 22(3):437-446(2010)Chen, Y., et al. Proteomics 7(14):2384-2397(2007)Shi, W., et al. J. Cell. Sci. 120 (PT 7), 1216-1224 (2007)

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$ 277.78
Cat# BP5120a
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