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TESC Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96BS2
Peptide ID 91113191
Additional Information
Gene ID 54997
Other Names Calcineurin B homologous protein 3, Tescalcin, TSC, TESC, CHP3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CHP3
Function Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.
Cellular Location Nucleus. Cytoplasm. Membrane. Cell membrane. Cell projection, lamellipodium. Cell projection, ruffle membrane. Note=Colocalizes with SLC9A1 at the plasma membrane
Tissue Location Expressed in mature megakaryocytes and polymorphonuclear granulocytes (at protein level). Abundantly expressed in heart. Also expressed at a lower level in adult testis and salivary gland, and in the placenta
Research Areas
Citations (0)

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Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation.


Bao, Y., et al. Gene Expr. Patterns 9(5):273-281(2009)Zaun, H.C., et al. J. Biol. Chem. 283(18):12456-12467(2008)Levay, K., et al. J. Clin. Invest. 117(9):2672-2683(2007)

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$ 80.00
Cat# BP5136b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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